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124 results found for 'dopamine'

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Glutamate: The Other Brain Chemical

Glutamate is the most abundant chemical in the brain, sending constant communication signals between nerve cells. Until recently, its role in Parkinson’s disease has been a mystery. That’s because most researchers’ attention has been focused on dopamine, another signalling chemical, whose loss is responsible for the stiffness, tremor and shakiness people with this disease experience. […]
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Redefining Parkinson's through a new biological lens

Traditionally, a diagnosis of Parkinson’s Disease relies on a clinical assessment by a doctor based on established clinical criteria. The clinical presentation of Parkinson’s often manifests late in disease progression. By this point, it is believed that significant underlying pathological biological processes and/or neurodegeneration have occurred.   In the dynamic landscape of Parkinson’s research, two groundbreaking […]
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2025 Research competition

Parkinson Canada would like to congratulate the applicants who have been successful in funding in our latest research competition and acknowledge the hard work and dedication to Parkinson’s research for all of our applicants. We look forward to continuing to engage with the exceptional Canadian research community and are excited to see the new applications […]
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Critical connections among brain cells

Making connections is not only important for people’s emotional well-being – it is also critical for healthy brains. As researchers are now discovering, the synapses, or the connections that convey signals and information from one neuron to another, may hold clues about what causes Parkinson’s disease. At the University of Montreal, molecular biologist Charles Ducrot […]
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What’s happening during Parkinson’s Awareness Month in Canada

April is Parkinson’s Awareness month, a time to focus on spreading knowledge, understanding and awareness of Parkinson’s disease. It’s also a time for celebrating the stories and courage of people living with Parkinson’s, their care partners and all the people contributing to Parkinson’s research.  There is a lot going on during Parkinson’s awareness month, here […]
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Changing the course of Parkinson’s: Exploring advancements in disease-modifying therapy research 

Parkinson’s affects more than 110,000 people across Canada and millions of people worldwide. While existing treatments help manage Parkinson’s symptoms, they fall short of slowing or stopping its progression. That’s where disease-modifying therapies (DMTs) come in—an exciting area of research that could transform Parkinson’s care. As research into DMTs advances, preparing the Parkinson’s community to […]
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A new target for deep brain stimulation that could directly improve walking

Stiffness, freezing and falling are among the problems that emerge when people have had Parkinson’s disease for some time. At the University of Calgary, PhD student Linda Kim is exploring ways to activate a group of cells in the brain called A13. She believes A13 might hold a reserved source of dopamine, the signaling chemical […]
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Dr. Suneil Kalia: The long quest for a Parkinson’s cure

It was an article about the late Wilder Penfield, a neurosurgery pioneer, that sparked a young Suneil Kalia’s quest to become a neurosurgeon three decades ago. “I was fascinated by the fact that the patient was awake while the doctor was operating on the brain,” says Dr. Kalia. It would take 20 years of post-secondary […]
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Scott Ryan's Parkinson's stem cell research garnering international recognition

When Scott Ryan travelled to Sweden earlier this year, he was keen to share the Parkinson’s research results from his small lab team at the University of Guelph. He was even more thrilled to have his poster presentation be one of five winning posters, out of 1,700, at the International Society for Stem Cell Research […]
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